Frequent detection of CBFA2T3::GLIS2 fusion and RAM-phenotype in pediatric non-Down syndrome acute megakaryoblastic leukemia: a possible novel relationship with aberrant cytoplasmic CD3 expression

Leuk Lymphoma. 2023 Feb;64(2):462-467. doi: 10.1080/10428194.2022.2140285. Epub 2022 Nov 8.

Authors

Yan Chen Wongworawat^{1

2}, Ghazaleh Eskandari¹, Amos Gaikwad³, Andrea N Marcogliese^{1

2}, Lizmery S Ferguson², Julienne Brackett⁴, Jyotinder N Punia^{1

2}, M Tarek Elghetany^{1

2}, Reshma Kulkarni³, Pulivarthi H Rao³, Jo Ringrose³, Dolores H Lopez-Terrada^{1

2

3

4}, Angshumoy Roy^{1

2

4}, Choladda V Curry^{1

2}, Kevin E Fisher^{1

2}

Affiliations

¹ Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.
² Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
³ Texas Children's Cancer Center Laboratories, Texas Children's Hospital, Houston, TX, USA.
⁴ Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.

PMID: 36346368
DOI: 10.1080/10428194.2022.2140285

No abstract available

Publication types

Letter

MeSH terms

Humans
Leukemia, Megakaryoblastic, Acute* / diagnosis
Leukemia, Megakaryoblastic, Acute* / genetics
Oncogene Proteins, Fusion / genetics
Oncogene Proteins, Fusion / metabolism
Repressor Proteins
Transcription Factors

Substances

Transcription Factors
Oncogene Proteins, Fusion
CBFA2T3 protein, human
Repressor Proteins