A 17-Year-Old Girl Diagnosed With STING-Associated Vasculopathy With Onset in Infancy (SAVI) After Lung Transplantation

Chest. 2022 Nov;162(5):e249-e252. doi: 10.1016/j.chest.2022.05.025.

Abstract

A 17-year-old girl received lung transplantation after chronic respiratory failure. She developed a fever (> 38 °C) once or twice weekly starting 2 months after surgery, and multiple papulopustules on the skin waxed and waned for 4 months. She then developed blood-tinged sputum. She had been treated with triple immunosuppressants, including prednisolone, tacrolimus, and mycophenolate mofetil after lung transplantation, and her symptoms appeared during prednisolone dose reduction.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lung Transplantation* / adverse effects
  • Mycophenolic Acid / therapeutic use
  • Prednisolone / therapeutic use
  • Tacrolimus
  • Vascular Diseases*

Substances

  • Mycophenolic Acid
  • Tacrolimus
  • Immunosuppressive Agents
  • Prednisolone