Photothermal Hydrogels for Promoting Infected Wound Healing

Macromol Biosci. 2023 Feb;23(2):e2200378. doi: 10.1002/mabi.202200378. Epub 2022 Nov 16.

Abstract

Photothermal therapies (PTT), with spatiotemporally controllable antibacterial capabilities without inducing resistance, have shown encouraging prospects in the field of infected wound treatments. As an important platform for PTT, photothermal hydrogels exhibit attractive advantages in the field of infected wound treatment due to their excellent biochemical properties and have been intensively explored in recent years. This review summarizes the progress of the photothermal hydrogels for promoting infected wound healing. Three major elements of photothermal hydrogels, i.e., photothermal materials, hydrogel matrix, and construction methods, are introduced. Furthermore, different strategies of photothermal hydrogels in the treatment of infected wounds are summarized. Finally, the challenges and prospects in the clinical treatment of photothermal hydrogels are discussed.

Keywords: Antibacterial; hydrogels; nanocomposites; photothermal therapies; wound healing.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents*
  • Humans
  • Hydrogels / pharmacology
  • Hydrogels / therapeutic use
  • Wound Healing
  • Wound Infection*

Substances

  • Anti-Bacterial Agents
  • Hydrogels