Early surgery or conservative management for asymptomatic severe aortic stenosis: Meta-analysis of RECOVERY and AVATAR

J Card Surg. 2022 Dec;37(12):5336-5340. doi: 10.1111/jocs.17130. Epub 2022 Nov 6.

Abstract

The standard practice for management for asymptomatic severe aortic stenosis with a normal left ventricular systolic function is conservative management with a few exceptions. This practice is challenged by two recent randomized controlled trials (RCT). All the prior data is observational. We performed a meta-analysis of these 2 RCTs to determine if early surgical aortic valve replacement in this patient population is beneficial compared with the standard conservative therapy.

Keywords: aorta and great vessels; valve repair/replacement.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Aortic Valve / surgery
  • Aortic Valve Stenosis* / surgery
  • Conservative Treatment
  • Heart Valve Prosthesis Implantation*
  • Heart Valve Prosthesis*
  • Humans