Rare-earth doped BiFe0.95Mn0.05O3 nanoparticles for potential hyperthermia applications

Astita Dubey; Soma Salamon; Supun B Attanayake; Syaidah Ibrahim; Joachim Landers; Marianela Escobar Castillo; Heiko Wende; Hari Srikanth; Vladimir V Shvartsman; Doru C Lupascu

doi:10.3389/fbioe.2022.965146

Rare-earth doped BiFe_0.95Mn_0.05O₃ nanoparticles for potential hyperthermia applications

Front Bioeng Biotechnol. 2022 Oct 18:10:965146. doi: 10.3389/fbioe.2022.965146. eCollection 2022.

Affiliations

¹ Institute for Materials Science and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Essen, Germany.
² Faculty of Physics and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Duisburg, Germany.
³ Department of Physics, University of South Florida, Tampa, FL, United States.

Abstract

Ionic engineering is exploited to substitute Bi cations in BiFe_0.95Mn_0.05O₃ NPs (BFM) with rare-earth (RE) elements (Nd, Gd, and Dy). The sol-gel synthesized RE-NPs are tested for their magnetic hyperthermia potential. RE-dopants alter the morphology of BFM NPs from elliptical to rectangular to irregular hexagonal for Nd, Gd, and Dy doping, respectively. The RE-BFM NPs are ferroelectric and show larger piezoresponse than the pristine BFO NPs. There is an increase of the maximum magnetization at 300 K of BFM up to 550% by introducing Gd. In hyperthermia tests, 3 mg/ml dispersion of NPs in water and agar could increase the temperature of the dispersion up to ∼39°C under an applied AC magnetic field of 80 mT. Although Gd doping generates the highest increment in magnetization of BFM NPs, the Dy-BFM NPs show the best hyperthermia results. These findings show that RE-doped BFO NPs are promising for hyperthermia and other biomedical applications.

Keywords: bismuth ferrite; doping; hyperthermia; magnetic; multiferroics; nanoparticles; piezoresponse; rare-earth.