Innovations in surgery to perform an ovarian drilling

J Gynecol Obstet Hum Reprod. 2023 Jan;52(1):102499. doi: 10.1016/j.jogoh.2022.102499. Epub 2022 Oct 31.

Abstract

Background: Ovarian drilling is a surgical technique for patients with dysovulatory polycystic ovarian syndrome. It is proposed as a second-line treatment in case of failure of medical treatment with Clomiphene citrate, Metformin or Letrozole. The 2020 Cochrane study comparing gonadotrophin stimulation and drilling has found the same pregnancy rate in both cases. The literature review concludes that 50% of spontaneous ovulation occurs in the first three months after drilling and 80% of pregnancy occurs in the following year. Ovarian drilling has also an impact on androgen excess and metabolic syndrome.

Aims: To update on the different surgical techniques to perform an ovarian drilling: surgical approach, energy used, operative risks.

Techniques: The objective of an ovarian drilling is to destroy 5% of the ovarian stroma. It is recommended to perform 8 to 10 perforations in each ovary with bipolar energy. Laser C02 and monopolar energy can be used but increase the risk of adhesion. The surgical approach is actually laparoscopic. Abdominal laparoscopy or transvaginal laparoscopy by vNOTES can be performed. The advantage of the second one is to provide an easier access to the pelvic cavity in case of obesity and patient have no abdominal scare. Both laparoscopic approaches allow an evaluation of tubal patency and adhesiolysis or fimbrioplasty. That it's not the case of an alternative technique: the fertiloscopy, due to coaxial instrumentation in spite of less rate of post-operative adhesions. Operative risks are abdominal adhesions, damage to neighboring organs and due to the general anesthesia.

Conclusion: Different surgical techniques exist to perform an ovarian drilling. The surgeon can choose the one that he masters best and that will involve the least risk for the patient. It is recommended to use bipolar energy.

Keywords: Drilling; Fertility; Hydrolaparoscopy; Laparoscopy; Polycystic ovary syndrome; Surgery; vNOTES.

MeSH terms

  • Clomiphene / therapeutic use
  • Female
  • Humans
  • Infertility, Female* / etiology
  • Infertility, Female* / surgery
  • Laparoscopy* / methods
  • Ovulation
  • Polycystic Ovary Syndrome* / complications
  • Polycystic Ovary Syndrome* / surgery
  • Pregnancy

Substances

  • Clomiphene