Immunoception: Defining brain-regulated immunity

Neuron. 2022 Nov 2;110(21):3425-3428. doi: 10.1016/j.neuron.2022.10.016.

Abstract

The emerging understanding of homeostatic neuroimmune interactions requires developing relevant terminology. In this NeuroView, Koren and Rolls define "immunoception" as the brain's bidirectional monitoring and control of immunity. They propose that the physiological trace storing immune-related information, the "immunengram," is distributed between the brain and memory cells residing in peripheral tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain* / physiology
  • Homeostasis
  • Neuroimmunomodulation* / physiology