A Rare Case of an Asymmetric Overgrowth Syndrome in a Kenyan African Child: A Case Report and Review of Literature

Diana A Okello; Joseph Mutio; Mary A Masiga; Symon Guthua; Nyambura Kariuki; Catherine Mutinda; Krishan Sarna; Ruth Wanjohi

doi:10.7759/cureus.29761

A Rare Case of an Asymmetric Overgrowth Syndrome in a Kenyan African Child: A Case Report and Review of Literature

Cureus. 2022 Sep 29;14(9):e29761. doi: 10.7759/cureus.29761. eCollection 2022 Sep.

Authors

Diana A Okello¹, Joseph Mutio², Mary A Masiga¹, Symon Guthua², Nyambura Kariuki³, Catherine Mutinda⁴, Krishan Sarna², Ruth Wanjohi⁵

Affiliations

¹ Department of Pedodontics and Preventive Dentistry, University of Nairobi, Nairobi, KEN.
² Department of Oral and Maxillofacial Surgery, Oral Pathology and Oral Medicine, Division of Oral and Maxillofacial Surgery, University of Nairobi, Nairobi, KEN.
³ Department of Paediatrics and Child Health, University of Nairobi, Nairobi, KEN.
⁴ Department of Genetics, University of Nairobi, Nairobi, KEN.
⁵ Department of Radiology, The Nairobi Hospital, Nairobi, KEN.

Abstract

Body overgrowth may be generalized or may affect certain areas. We present a seven-year-old African male with progressive, asymmetric, postnatal overgrowth of the left side of his face and left upper limb. The impression of proteus syndrome (PS) was made based on established clinical diagnostic criteria presented in the literature. Our objective is to highlight the diagnosis based on clinical features, investigations, and a multidisciplinary approach to the management of proteus syndrome.

Keywords: akt1; assymetric overgrowth; hemihypertrophy; overgrowth syndrome; proteus syndrome.

Publication types

Case Reports