A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications

Cureus. 2022 Sep 29;14(9):e29756. doi: 10.7759/cureus.29756. eCollection 2022 Sep.

Abstract

Aspergillus is a fungal genus found worldwide, which causes infection most commonly in the respiratory system and in other systems, including the central nervous system. Fungal species, such as Aspergillus fumigatus or flavus, are more common in immunocompromised patient populations, such as those taking immunosuppressants post-transplantation, those on long-term corticosteroids, or those with immunodeficiencies such as AIDS. In this paper, we describe a rare case of aspergillosis that occurred due to a history of taking corticosteroids to treat arthritis pain in a patient with type 2 diabetes. Given the rise in antifungal-resistant species and environmental changes, it is noteworthy for further research to be conducted on new treatment plans and the management of such fungal infections to prepare against opportunistic infections caused by Aspergillus in the future.

Keywords: anti-fungal resistance; aspergillus; cerebral aspergillosis; healthcare implications; immunosuppressed.

Publication types

  • Case Reports