Demographics, Clinicopathological Profile of Oral Lichen Planus of South Kerala Population: A Cross-Sectional Study

Aswathy K Vijayan; Arvind Muthukrishnan; Aparna M Nair; Joyal Jose Baby

doi:10.7759/cureus.29688

Demographics, Clinicopathological Profile of Oral Lichen Planus of South Kerala Population: A Cross-Sectional Study

Cureus. 2022 Sep 28;14(9):e29688. doi: 10.7759/cureus.29688. eCollection 2022 Sep.

Authors

Aswathy K Vijayan¹, Arvind Muthukrishnan², Aparna M Nair³, Joyal Jose Baby⁴

Affiliations

¹ Department of Oral Medicine and Radiology, PMS College of Dental Science and Research, Thiruvananthapuram, IND.
² Department of Oral Medicine & Radiology, Saveetha Dental College & Hospital, Chennai, IND.
³ Department of Periodontology, PMS College of Dental Science and Research, Thiruvananthapuram, IND.
⁴ Department of Prosthodontics, PMS College of Dental Science and Research, Thiruvananthapuram, IND.

Abstract

Background: Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory lesion of unknown cause. The buccal mucosa is the most frequently affected anatomic site and the lesion is bilateral. The objective of this retrospective study was to investigate the epidemiological and clinical characteristics of 250 OLP patients in South Kerala. This was done by figuring out these patients' epidemiological and clinical characteristics. Materials and methods: In the present study, patients who reported between September 2018 and December 2021 were selected employing the diagnostic criteria consistent with the WHO classification of OLP. Data of all the patient's characteristic features were collected and evaluated using the Statistical Package for the Social Sciences (SPSS) software for statistical analysis.

Results: Out of 250 patients, 52% were females and 48% were males. Reticular (n = 145, 58%) and erosive forms (n = 105, 42%) were the two clinical presentations of the lesions that were most consistently observed. The age group of 25-34 years reported the highest number of cases (n = 71, 28.4%). According to the chi-square test, there were statistically highly significant differences between the hyperpigmentation, age, and type of OLP. While 43.2% (n = 108) of cases reported a burning sensation, pain, or soreness, 56.8% (n = 142) of cases were asymptomatic. There were statistically significant differences between the type of OLP and the reported symptoms (p = 0.001). Mild to moderate dysplastic changes were documented in 5.6% during the follow-up period. A successful treatment outcome with topical steroid administration was recorded in the study sample.

Conclusion: It was apparent that patients typically have bilateral lesions involving the buccal and labial mucosa, manifesting with varying degrees of oral discomfort. Although patients frequently have more than one variant of OLP, the lesions are typically reticular or erosive in nature. A meticulous follow-up is crucial to determine its malignant change.

Keywords: dysplasia; erosive; hyperpigmentation; oral lichen planus; reticular.