Strengthening the link between mitophagy and Parkinson's disease

Brain. 2022 Dec 19;145(12):4154-4156. doi: 10.1093/brain/awac405.

Abstract

This scientific commentary refers to ‘Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci’ by Soutar et al. (https://doi.org/10.1093/brain/awac325); and ‘DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy’ by Imberechts et al. (https://doi.org/10.1093/brain/awac313).

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Humans
  • Mitophagy*
  • Parkinson Disease*
  • Protein Kinases
  • Ubiquitin-Protein Ligases

Substances

  • Ubiquitin-Protein Ligases
  • Protein Kinases