Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System

Physiology (Bethesda). 2023 Mar 1;38(2):0. doi: 10.1152/physiol.00022.2022. Epub 2022 Nov 1.

Abstract

Developmental hypoxia has profound and persistent effects on the vertebrate cardiovascular system, but the nature, magnitude, and long-term outcome of the hypoxic consequences are species specific. Here we aim to identify common and novel cardiovascular responses among vertebrates that encounter developmental hypoxia, and we discuss the possible medical and ecological implications.

Keywords: embryo; fetus; heart; hypoxia; programming.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular System*
  • Heart / physiology
  • Humans
  • Hypoxia
  • Vertebrates