A review of high-intensity focused ultrasound as a novel and non-invasive interventional radiology technique

J Interv Med. 2022 Jun 22;5(3):127-132. doi: 10.1016/j.jimed.2022.06.004. eCollection 2022 Aug.

Abstract

High-intensity focused ultrasound (HIFU) is a non-invasive interventional radiology technology, which has been generally accepted in clinical practice for the treatment of benign and malignant tumors. HIFU can cause targeted tissue coagulative necrosis and protein denaturation by thermal or non-thermal effects, guided by diagnostic ultrasound or magnetic resonance imaging, without destruction of the normal adjacent tissue, under sedation or general anesthesia. HIFU has become an important alternative to standard treatments of solid tumors, including surgery, radiation, and medications. The aim of this review is to describe the development, principle, devices, and clinical applications of HIFU.

Keywords: Clinical application; HIFU; Transducers; Tumor.