Radiotherapy for meningiomas

William C Chen; Haley K Perlow; Abrar Choudhury; Minh P Nguyen; Kanish Mirchia; Mark W Youngblood; Calixto-Hope G Lucas; Joshua D Palmer; Stephen T Magill; David R Raleigh

doi:10.1007/s11060-022-04171-9

Radiotherapy for meningiomas

J Neurooncol. 2022 Nov;160(2):505-515. doi: 10.1007/s11060-022-04171-9. Epub 2022 Oct 31.

Authors

William C Chen^{1

2}, Haley K Perlow³, Abrar Choudhury^{4

5}, Minh P Nguyen^{4

5}, Kanish Mirchia^{4

5

6}, Mark W Youngblood⁷, Calixto-Hope G Lucas⁸, Joshua D Palmer³, Stephen T Magill⁷, David R Raleigh^{9

10}

Affiliations

¹ Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, 94143, USA. william.chen@ucsf.edu.
² Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, 94143, USA. william.chen@ucsf.edu.
³ Department of Radiation Oncology, Ohio State University, Columbus, OH, 43210, USA.
⁴ Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, 94143, USA.
⁵ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, 94143, USA.
⁶ Department of Pathology, University of California San Francisco, San Francisco, CA, 94143, USA.
⁷ Department of Neurological Surgery, Northwestern University, Chicago, IL, 60611, USA.
⁸ Department of Pathology, Johns Hopkins University, Baltimore, MD, 21287, USA.
⁹ Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, 94143, USA. david.raleigh@ucsf.edu.
¹⁰ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, 94143, USA. david.raleigh@ucsf.edu.

Abstract

Meningiomas are the most common primary central nervous system neoplasm. Despite promising recent progress in elucidating the genomic landscape and underlying biology of these histologically, molecularly, and clinically diverse tumors, the mainstays of meningioma treatment remain maximal safe resection and radiation therapy. The aim of this review of meningioma radiotherapy is to provide a concise summary of the history, current evidence, and future for application of radiotherapy in meningioma treatment.

Keywords: Anaplastic; Atypical; DOTATATE; Meningioma; Molecular; Radiation; Radiotherapy.

Radiotherapy for meningiomas

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Grants and funding