An improved U-net based retinal vessel image segmentation method

Heliyon. 2022 Oct 21;8(10):e11187. doi: 10.1016/j.heliyon.2022.e11187. eCollection 2022 Oct.

Abstract

Diabetic retinopathy is not just the most common complication of diabetes but also the leading cause of adult blindness. Currently, doctors determine the cause of diabetic retinopathy primarily by diagnosing fundus images. Large-scale manual screening is difficult to achieve for retinal health screen. In this paper, we proposed an improved U-net network for segmenting retinal vessels. Firstly, due to the lack of retinal data, pre-processing of the raw data is required. The data processed by grayscale transformation, normalization, CLAHE, gamma transformation. Data augmentation can prevent overfitting in the training process. Secondly, the basic network structure model U-net is built, and the Bi-FPN network is fused based on U-net. Datasets from a public challenge are used to evaluate the performance of the proposed method, which is able to detect vessel SP of 0.8604, SE of 0.9767, ACC of 0.9651, and AUC of 0.9787.

Keywords: Bi-FPN; Deep learning; Retinal vessel segmentation; U-net.