A Chinese classical prescription Qianjinweijing Decoction in treatment of lung cancer: An overview

Biomed Pharmacother. 2022 Dec:156:113913. doi: 10.1016/j.biopha.2022.113913. Epub 2022 Oct 26.

Abstract

Lung cancer is one of the most common malignant tumors in the world, and its incidence and mortality rate rank among the top malignant tumors worldwide, which has become an important killer threatening human survival rate and well-being. Modern medical treatment for lung cancer is mainly based on surgery and radiotherapy, with gene, targeted drugs and immunotherapy as auxiliary treatments, which are effective, but there are problems such as postoperative recurrence, resistance to radiotherapy, toxic side effects and poor compliance. In recent years, with the continuous development of TCM, TCM is popular among physicians and patients for its high efficiency, low toxicity, low side effects and economic benefits, etc. As a classical TCM formula, Qianjin Weijin Decoction(QJWJ) has certain value in the treatment of lung cancer. This paper summarizes and analyzes the clinical research, molecular mechanism, pharmacological effects and chemical composition of QJWJ in the treatment of lung cancer, in order to provide more ideas and theoretical basis for the treatment of lung cancer with QJWJ.

Keywords: Clinical study; Lung cancer; Molecular mechanism; Pharmacology; Qianjinweijing Decoction.

Publication types

  • Review

MeSH terms

  • China
  • Drugs, Chinese Herbal* / pharmacology
  • Humans
  • Lung Neoplasms* / drug therapy
  • Medicine, Chinese Traditional
  • Prescriptions

Substances

  • Drugs, Chinese Herbal