Harnessing synthetic biology for mushroom farming

Gen Zou; Jens B Nielsen; Yongjun Wei

doi:10.1016/j.tibtech.2022.10.001

Harnessing synthetic biology for mushroom farming

Trends Biotechnol. 2023 Apr;41(4):480-483. doi: 10.1016/j.tibtech.2022.10.001. Epub 2022 Oct 26.

Authors

Gen Zou¹, Jens B Nielsen², Yongjun Wei³

Affiliations

¹ Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Fengxian, 201403, Shanghai, PR China.
² BioInnovation Institute, Ole Maaløes Vej 3, DK2200 Copenhagen N, Denmark; Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296 Gothenburg, Sweden.
³ School of Pharmaceutical Sciences, Laboratory of Synthetic Biology, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450051, PR China. Electronic address: yongjunwei@zzu.edu.cn.

PMID: 36307231
DOI: 10.1016/j.tibtech.2022.10.001

Abstract

Recent advances in synthetic biology have transformed mushroom farming from a focus on traditional cultivation to comprehensive applications based on cutting-edge biotechnologies. Synthetic biology has promising applications in this field, including precision breeding, mining biosynthetic gene clusters, developing mushroom chassis cells, and constructing cell factories for high value-added products.

Keywords: BioPart; cell factory; chassis; genome editing; mushroom; synthetic biology.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Agaricales* / genetics
Agriculture
Biotechnology
Plant Breeding
Synthetic Biology*