Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy

Biomed Res Int. 2022 Oct 18:2022:6171687. doi: 10.1155/2022/6171687. eCollection 2022.

Abstract

This study is aimed at testing the hypothesis that serum analysis of high-sensitivity troponin T in neonates may serve as a diagnostic tool to predict the risk of gestational diabetes mellitus (GDM). 86 newborns were studied and stratified into two groups: healthy group; newborns with body weight ≥ 10th percentile, born in good condition (APG 8-10pts) of pregnancy not complicated by diabetes, and the GDM group; neonates born to mothers with type 1 or type 2 diabetes. Results. The study revealed minimal troponin levels in GDM, and healthy groups equal to 0.02 ng/mL and 0.028 ng/mL, respectively. The GDM group is defined by an interquartile range of hs-TnT higher than the healthy group. This study confirms previously reported upper levels of troponin in healthy children. There are possible health problems that can appear during infancy and influence the further development of a child affected by GDM.

MeSH terms

  • Child
  • Diabetes Mellitus, Type 2* / complications
  • Diabetes, Gestational*
  • Female
  • Humans
  • Infant, Newborn
  • Mothers
  • Pregnancy
  • Troponin T

Substances

  • Troponin T