Nanoparticle Diagnostics and Theranostics in the Clinic

J Nucl Med. 2022 Dec;63(12):1802-1808. doi: 10.2967/jnumed.122.263895. Epub 2022 Oct 27.

Abstract

Nanoparticles possess unique features that may be useful for disease diagnosis and therapy. Preclinically, many different nanodiagnostics have been explored, but only a few have made it to the market. We here provide an overview of nanoparticle-based imaging agents currently used and evaluated in the clinic and discuss preclinical progress and translational avenues for the use of nanoparticles for diagnostic and theranostic applications.

Keywords: molecular imaging; nanodiagnostics; nanomedicine; nanoparticles; oncology; theranostics.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Nanoparticles* / therapeutic use
  • Neoplasms* / therapy
  • Precision Medicine / methods
  • Theranostic Nanomedicine / methods