Fluoride Intake and Salivary Fluoride Retention after Using High-Fluoride Toothpaste Followed by Post-Brushing Water Rinsing and Conventional (1400-1450 ppm) Fluoride Toothpastes Used without Rinsing

Int J Environ Res Public Health. 2022 Oct 14;19(20):13235. doi: 10.3390/ijerph192013235.

Abstract

This study aimed to compare the fluoride intake and salivary fluoride levels after brushing with conventional (1400-1450 ppm) fluoride toothpaste containing different fluoride agents: amine fluoride (AmF), sodium fluoride (NaF), sodium monofluorophosphate (SMFP), potassium fluoride (KF), and a high-fluoride (5000 ppm) toothpaste containing NaF. Fourteen volunteers took part in the study. They were instructed to brush and spit without rinsing after using conventional toothpaste or brush and rinse with water after using a high-fluoride toothpaste. Fluoride concentrations were determined using ion-selective fluoride (09-37 type) in the saliva samples before and after procedures. Fluoride intake was estimated based on fluoride recovered after brushing. Additionally, the amount of fluoride present in the oral fluids and lost during the rapid clearance phase after toothbrushing was calculated based on salivary fluoride levels and saliva flow immediately after brushing. Salivary fluoride after using high-fluoride toothpaste was significantly higher than those observed after conventional products. Two hours after brushing, salivary fluoride concentrations did not differ significantly from baseline values (p > 0.05) unless a high-fluoride product was used. Results indicate that by refraining from rinsing after brushing with conventional toothpaste, we cannot obtain fluoride retention in saliva as with high-fluoride toothpaste. Fluoride ingestion was higher after using a high-fluoride product.

Keywords: fluoride gel; fluoride intake; fluoride retention; salivary fluoride; toothpaste.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amines
  • Cariostatic Agents
  • Fluorides*
  • Humans
  • Mouthwashes
  • Saliva / chemistry
  • Sodium Fluoride
  • Toothbrushing
  • Toothpastes*
  • Water

Substances

  • Toothpastes
  • Fluorides
  • Sodium Fluoride
  • Cariostatic Agents
  • Water
  • Mouthwashes
  • Amines