Graphene and Its Derivatives: Synthesis and Application in the Electrochemical Detection of Analytes in Sweat

Biosensors (Basel). 2022 Oct 21;12(10):910. doi: 10.3390/bios12100910.

Abstract

Wearable sensors and invasive devices have been studied extensively in recent years as the demand for real-time human healthcare applications and seamless human-machine interaction has risen exponentially. An explosion in sensor research throughout the globe has been ignited by the unique features such as thermal, electrical, and mechanical properties of graphene. This includes wearable sensors and implants, which can detect a wide range of data, including body temperature, pulse oxygenation, blood pressure, glucose, and the other analytes present in sweat. Graphene-based sensors for real-time human health monitoring are also being developed. This review is a comprehensive discussion about the properties of graphene, routes to its synthesis, derivatives of graphene, etc. Moreover, the basic features of a biosensor along with the chemistry of sweat are also discussed in detail. The review mainly focusses on the graphene and its derivative-based wearable sensors for the detection of analytes in sweat. Graphene-based sensors for health monitoring will be examined and explained in this study as an overview of the most current innovations in sensor designs, sensing processes, technological advancements, sensor system components, and potential hurdles. The future holds great opportunities for the development of efficient and advanced graphene-based sensors for the detection of analytes in sweat.

Keywords: graphene; health monitoring; invasive; non-invasive; sensors; wearable.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Glucose / analysis
  • Graphite* / chemistry
  • Humans
  • Monitoring, Physiologic
  • Sweat / chemistry
  • Wearable Electronic Devices*

Substances

  • Graphite
  • Glucose

Grants and funding

This research received no external funding.