Clinical Application of Thromboelastography in Acute Ischemic Stroke

Clin Appl Thromb Hemost. 2022 Jan-Dec:28:10760296221131801. doi: 10.1177/10760296221131801.

Abstract

Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay in waiting for the results of conventional coagulation tests in candidate patients for intravenous thrombolysis therapy. Heterogeneous responses to antiplatelet, intravascular thrombolysis, and endovascular therapies also worsen the situation. Thromboelastography (TEG), as a global and portable detection method for hemostasis, facilitates clinicians in disease monitoring, treatment evaluation, and prognosis prediction in AIS. In this narrative review, we provided a comprehensive summary of the clinical application of TEG in ischemic stroke and gave insights to further studies.

Keywords: acute ischemic stroke; clinical application; thromboelastography.

Publication types

  • Review

MeSH terms

  • Blood Coagulation Tests
  • Brain Ischemia*
  • Humans
  • Ischemic Stroke*
  • Stroke*
  • Thrombelastography
  • Thrombolytic Therapy / methods
  • Treatment Outcome