Lung Transplantation for Multiple Giant Hamartomas: First Case Report and Review of the Literature

Transplant Proc. 2022 Nov;54(9):2506-2508. doi: 10.1016/j.transproceed.2022.09.008. Epub 2022 Oct 22.

Abstract

Background: To assess lung transplant as a solution for a rare complication of giant lung hamartoma, in which surgical resection was discouraged because of severe underlying chronic lung disease.

Methods: A 54-year-old woman had an episode of severe acute hemoptysis. Imaging techniques showed 2 masses in the right lung as hamartomas and severe pulmonary emphysema. After resolution of the acute episode of hemoptysis, the case could have been solved with a right pneumonectomy; however, a single-lung transplant was performed because of the underlying chronic obstructive pulmonary disease.

Results: The outcome of the surgery was satisfactory, although a second operation was required because of bleeding. The patient was discharged and currently has a good quality of life, with no recurrence of the disease. The pathologic anatomy of the surgical specimen confirmed the diagnosis of multiple giant hamartomas.

Conclusions: Lung transplant could be a feasible procedure to treat life-threatening complications of benign tumors in selected patients with pulmonary end-stage disease.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Female
  • Hamartoma* / complications
  • Hamartoma* / diagnostic imaging
  • Hamartoma* / surgery
  • Hemoptysis
  • Humans
  • Lung Transplantation* / methods
  • Middle Aged
  • Pneumonectomy / methods
  • Quality of Life