Early diagnosis of systemic scleroderma

Vnitr Lek. 2022 Fall;68(5):285-289. doi: 10.36290/vnl.2022.061.

Abstract

Systemic scleroderma (SSc) is a systemic immune-mediated connective tissue disease characterized by fibroproductive changes in connective tissue and microvascular disorders. The disease affects the skin, musculoskeletal system and internal organs. It is a disease with a significant rate of morbidity and mortality, significantly worsening the quality of life of patients. Early initiation of therapy is necessary to prevent disease progression. This review article discusses the current possibilities of early diagnosis of systemic scleroderma.

Keywords: diagnosis; diagnostics; early forms of scleroderma; systemic scleroderma; systemic sclerosis.

Publication types

  • Review

MeSH terms

  • Connective Tissue Diseases*
  • Early Diagnosis
  • Humans
  • Quality of Life
  • Scleroderma, Systemic* / diagnosis