Chitosan based architectures as biomedical carriers

Prem Prakash Sharma; Shakshi Bhardwaj; Aaftaab Sethi; Vijay K Goel; Maria Grishina; Poonam; Brijesh Rathi

doi:10.1016/j.carres.2022.108703

Chitosan based architectures as biomedical carriers

Carbohydr Res. 2022 Dec:522:108703. doi: 10.1016/j.carres.2022.108703. Epub 2022 Oct 17.

Authors

Prem Prakash Sharma¹, Shakshi Bhardwaj¹, Aaftaab Sethi¹, Vijay K Goel², Maria Grishina³, Poonam⁴, Brijesh Rathi⁵

Affiliations

¹ Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, 110007, India.
² School of Physical Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
³ South Ural State University, Laboratory of Computational Modelling of Drugs, Pr. Lenina, 76, 454080, Russia.
⁴ Department of Chemistry, Miranda House, University of Delhi, Delhi, 110007, India. Electronic address: poonam.chemistry@mirandahouse.ac.in.
⁵ Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, 110007, India; South Ural State University, Laboratory of Computational Modelling of Drugs, Pr. Lenina, 76, 454080, Russia. Electronic address: brijeshrathi@hrc.du.ac.in.

PMID: 36283262
DOI: 10.1016/j.carres.2022.108703

Abstract

In the recent past, chitosan demonstrated intriguing applications in the different domains of biomedical science, probably due to its biodegradability, biocompatibility, minimal toxicity, cost-effectiveness, and easy-going synthetic procedures. Chitosan is the second most prevalent amino polysaccharide after cellulose, generated from a deacetylated version of chitin. This short review briefly explains the preparation methods for chitosan from chitin and its role as a drug carrier for biomedical applications.

Keywords: Biodegradable; Biomedical applications; Chitosan; Drug delivery; Polysaccharide.

MeSH terms

Chitin
Chitosan*
Drug Carriers
Polysaccharides

Substances

Chitosan
Chitin
Drug Carriers
Polysaccharides