PROTAC vaccine: A new way to live attenuated vaccines

Clin Transl Med. 2022 Oct;12(10):e1081. doi: 10.1002/ctm2.1081.

Zhen Li¹, Haiqing Bai², Xuetong Xi^{1

3}, Wen-Xia Tian⁴, John Z H Zhang¹, Demin Zhou⁵, Longlong Si^{1

3}

¹ CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
² Xellar Biosystems Inc, Cambridge, Massachusetts, USA.
³ College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
⁴ College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, China.
⁵ State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.

No abstract available

Keywords: PROTAC; influenza; live attenuated vaccine; targeted protein degradation.

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