Analysis of risk factors for recurrence and prognosis of adhesive small bowel obstruction

Abstract

Objective: The recurrence of adhesive small bowel obstruction (ASBO) limits the effectiveness of clinical treatments, making its significant clinical issues. Clinical features, perioperative parameters, and postoperative outcomes were retrospectively analyzed, to provide basis for screening the high risk factors in patients of recurrent ASBO.

Methods: A review of medical records of patients with ASBO at Chongqing University Central Hospital, from 1 January 2015 to 31 December 2019 was conducted. We compared the clinical characteristics, intra-operative findings, and history surgery of ASBO "relapse-free" and relapsing patients. Logistic proportional hazard model was used to identify recurrence risks.

Results: Based on specified inclusion and exclusion criteria, a total of 279 patients were included in this study. Participants' mean age was 63.0 (13.1) years; 49.4% (138 of 279) of them were male. Using multivariate Logistic regression analysis, the history of emergency abdominal surgery (hazard ratio, 0.241, p < 0.0001) was significantly associated with recurrence, as were multiple abdominal surgeries (hazard ratio, 0.250, p < 0.0001) and diabetes mellitus (hazard ratio, 0.182, p < 0.0001). Patients with recurrence, who underwent surgery had longer operative times, blood loss, and a higher incidence of wound complications than those without recurrence.

Conclusion: The history of emergency abdominal surgery, multiple abdominal surgeries, and diabetes mellitus independently increased the chances of ASBO recurrence. Patients with ASBO recurrence had a higher incidence of postoperative complications.

Keywords: Adhesive small bowel obstruction; Diabetes mellitus; Emergency surgery; Multiple abdominal surgeries; Risk factor.