For decades, the literature was skeptical about the feasibility of motor rehabilitation and its impact, as well as that of physical activity (PA), in subjects with major neurocognitive disorders (MNCD), including Alzheimer's disease. Now, authors report several benefits of PA, both physical and cognitive, by promoting brain perfusion, neurogenesis and synaptic plasticity, as well as decreasing oxidative stress and inflammation. PA should be recommended in cases of TNCM.
Keywords: Alzheimer’s disease; activité physique; major neurocognitive disorder; maladie d’Alzheimer; motor rehabilitation; physical activity; rééducation motrice; trouble neurocognitif majeur.
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