Evaluation of dry eye symptoms and risk factors among medical students in Serbia

PLoS One. 2022 Oct 24;17(10):e0275624. doi: 10.1371/journal.pone.0275624. eCollection 2022.

Abstract

Background: Dry eye is a multifactorial disease defined less than 30 years ago. It is a relatively common disorder, affected by a number of well-known risk factors. Dry eye can be challenging to diagnose because of the possible discrepancy between patients' symptoms and clinical signs, and its overlap with other ocular surface diseases. Literature-wise, dry eye is usually associated with age and therefore investigated within older populations. Recently, studies focusing on young adult and student populations have demonstrated a higher prevalence of dry eye than previously expected.

Aim: The study aims to determine the frequency of dry eye symptoms in the student population, and the impact of students' activities and habits as potential risk factors.

Methodology: Our study involved 397 students from the medical school at the University of Belgrade, Serbia. Students were asked to complete an online survey that addressed general information, health, habits, and routine in everyday use of electronic devices. In addition, students completed a standard Ocular Surface Disease Index questionnaire.

Results: The prevalence of dry eye was 60.5% (240/397) in our study population. Contact lens wear (p<0.001), allergies (p = 0.049) and increased number of hours per day using VD devices for studying purposes (p = 0.014) were associtated with a higher risk of dry eye disease. Risk factors that did not significantly impact dry eye were the use of oral contraceptives, smoking, systemic diseases, year of study and sex.

Conclusion: In our study, the prevalence of dry eye disease was similar or slightly higher than in previous studies among young adults. In addition, contact lenses, allergies and visual display devices were associated with the development of the dry eye.

MeSH terms

  • Contraceptives, Oral
  • Cross-Sectional Studies
  • Dry Eye Syndromes* / diagnosis
  • Dry Eye Syndromes* / epidemiology
  • Dry Eye Syndromes* / etiology
  • Female
  • Humans
  • Hypersensitivity* / complications
  • Risk Factors
  • Serbia / epidemiology
  • Students, Medical*
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Contraceptives, Oral

Associated data

  • figshare/10.6084/m9.figshare.21235578
  • figshare/10.6084/m9.figshare.21235599
  • figshare/10.6084/m9.figshare.21235626

Grants and funding

The author(s) received no specific funding for this work.