Herb-induced hepatitis secondary to artemisinin: A case report

Jiwei Zhan; Meilin Ding; Jin Li; Lei Su

doi:10.3389/fmed.2022.1033906

Herb-induced hepatitis secondary to artemisinin: A case report

Front Med (Lausanne). 2022 Oct 6:9:1033906. doi: 10.3389/fmed.2022.1033906. eCollection 2022.

Authors

Jiwei Zhan^{1

2}, Meilin Ding², Jin Li², Lei Su²

Affiliations

¹ Department of Geriatrics, Central People's Hospital of Zhanjiang, Zhanjiang, China.
² Department of Geriatrics, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Abstract

This report describes a rare case of severe liver injury secondary to a herbal supplement containing artemisinin. The patient received plasma exchange with bilirubin filtration adsorption therapy. The case is unique in its severe cholestasis. Bilirubin decreased to baseline after 62 days. This will help to improve clinicians' awareness of the diagnosis and treatment of drug-induced liver injury.

Keywords: artemisinin; cholestatic hepatitis; drug-induced liver injury; jaundice; plasma exchange (PE).

Publication types

Case Reports