Surgical Management of Peripheral Ulcerative Keratitis: Update on Surgical Techniques and Their Outcome

Clin Ophthalmol. 2022 Oct 19:16:3547-3557. doi: 10.2147/OPTH.S385782. eCollection 2022.

Abstract

Peripheral ulcerative keratitis (PUK) is an inflammatory, necrotic condition in the peripheral cornea which may end in corneal perforation and visual morbidity if not treated adequately. PUK can occur due to infectious or non-infectious causes. Early cases need medical therapy, both locally and systemically (for some cases). However, advanced PUK may necessitate surgical removal of inciting cause of the pathology and maintaining tectonic stability. Such surgical treatment, including corneal transplantations, may be used in an emergency setting or for visual rehabilitation following preliminary stabilization of the affected cornea. The outcome of these surgeries need to be analyzed to understand the long-term visual prognosis of such eyes. This is an attempt to analyze surgical modalities in the management of PUK and their outcomes.

Keywords: amniotic membrane; keratoplasty; peripheral ulcer; tissue adhesive.

Publication types

  • Review

Grants and funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.