Antioxidant nanozymes for prevention of diseased kidney from failure

Kidney Int. 2022 Nov;102(5):961-963. doi: 10.1016/j.kint.2022.08.003.

Abstract

Oxidative stress is a state of excessive free radicals and is commonly found with diseased kidneys. Therefore, development of antioxidant-based therapy has been of great interest to biomedical scientists for kidney disease management. One of the drawbacks of using natural antioxidants is their low bioavailability, which limits their anti-free radical efficacy. This commentary discusses novel antioxidant gold-platinum nanoparticles and their potential for prevention of kidney failure in patients who are diagnosed with chronic kidney disease.

Publication types

  • Comment

MeSH terms

  • Antioxidants* / metabolism
  • Antioxidants* / therapeutic use
  • Free Radicals
  • Gold
  • Humans
  • Kidney / metabolism
  • Metal Nanoparticles*
  • Oxidative Stress
  • Platinum

Substances

  • Antioxidants
  • Platinum
  • Free Radicals
  • Gold