Optimisation of the additive manufacturing parameters of polylactic acid (PLA) cellular structures for biomedical applications

J Mech Behav Biomed Mater. 2022 Dec:136:105447. doi: 10.1016/j.jmbbm.2022.105447. Epub 2022 Sep 9.

Abstract

Fused deposition modelling (FDM) is an additive manufacturing technology used to create functional and complex geometries directly from computer-generated models. This technique can be utilised to generate cellular structures with controllable pore size, pore shape, and porosity. Cellular structures are fundamental in orthopaedics scaffolds because of its low elastic modulus, high compressive strength, and adequate cell accommodation spaces. This paper aims at investigating and optimising the FDM additive manufacturing process parameters of polylactic Acid (PLA) for two lattice structures namely Schoen Gyroid and Schwarz Primitive. The effect of additive manufacturing critical process parameters including layer height, flow rate, and print speed on the geometrical accuracy and compressive strength of the specimens were analysed. In addition, other parameters that have minimal effect on the geometrical accuracy of the printed parts were discussed. A Full Factorial Analysis (FFA) using Minitab software was undertaken to identify the perfect combination of printing parameters to provide the most geometrically accurate structure. In this study, samples of the Schoen Gyroid and the Schwarz Primitive lattices and a solid control cylinder were 3D printed using the ideal printing combination to assess the manufacturability, the geometrical accuracy, and the mechanical behaviour of both designs. It was found that the optimised FDM process parameters for the studied cellular structures were a layer height of 0.16 mm, a printing speed of 50 mm/s and a flow rate of 90%. As a result of using these parameters, the solid, Schoen Gyroid and Schwarz Primitive specimens demonstrated elastic moduli values of 951 MPa, 264 MPa, and 221 MPa, respectively. In addition, the Schoen Gyroid and the Schwarz Primitive have reached their stress limits at around 8.68 MPa and 7.06 MPa, respectively. It was noticed that the Schoen Gyroid structure exhibited ∼ 18% higher compressive strength and ∼ 16% higher elastic modulus compared to the Schwarz Primitive structure for the same volume fraction of porosity, overall dimensions, and the manufacturing process parameters. Although both structures revealed mechanical properties that fall within the range of the human trabecular bone, but Schoen Gyroid exhibited improved structural integrity performance that is evident by its post-yield behaviour.

Keywords: Additive manufacturing (AM); Biodegradable polylactic acid (PLA); Cellular structures; Fused deposition modelling (FDM); Orthopaedics scaffolds; Schoen gyroid; Schwarz primitive.

MeSH terms

  • Cancellous Bone
  • Humans
  • Polyesters* / chemistry
  • Porosity
  • Tissue Scaffolds* / chemistry

Substances

  • poly(lactide)
  • Polyesters