Urinary Biomarkers of Kidney Disease in Dogs and Cats

Mary Nabity; Jessica Hokamp

doi:10.1016/j.cvsm.2022.07.006

Urinary Biomarkers of Kidney Disease in Dogs and Cats

Vet Clin North Am Small Anim Pract. 2023 Jan;53(1):53-71. doi: 10.1016/j.cvsm.2022.07.006. Epub 2022 Oct 19.

Authors

Mary Nabity¹, Jessica Hokamp²

Affiliations

¹ Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4467, USA.
² Department of Veterinary Biosciences, College of Veterinary Medicine, Ohio State University, 1925 Coffey Road, Columbus, OH 43210, USA. Electronic address: hokamp.1@osu.edu.

PMID: 36270837
DOI: 10.1016/j.cvsm.2022.07.006

Abstract

A variety of urinary markers of the renal disease show promise for the identification of glomerular and tubular damage and monitoring treatment. Most of the markers are currently not widely available, and all could benefit from further study. This review summarizes recent studies on urinary biomarkers of renal disease in dogs and cats.

Keywords: C-reactive protein (CRP); Clusterin; Cystatin; Gamma-glutamyl transpeptidase (GGT); Immunoglobulin G (IgG); Kidney injury molecule-1 (KIM-1); Neutrophil gelatinase-associated lipocalin (NGAL); Retinol-binding protein (RBP).

Publication types

Review

MeSH terms

Animals
Biomarkers
Cat Diseases* / diagnosis
Cats
Dog Diseases* / diagnosis
Dogs
Kidney Diseases* / diagnosis
Kidney Diseases* / veterinary
Lipocalin-2

Substances

Lipocalin-2
Biomarkers