BRCA1 protects against its own fragility

Mol Cell. 2022 Oct 20;82(20):3757-3759. doi: 10.1016/j.molcel.2022.09.023.

Abstract

Deshpande et al. (2022) demonstrate that BRCA1, a tumor suppressor tasked with protecting the genome, is encoded by a gene that is intrinsically fragile.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • BRCA1 Protein* / genetics
  • Genes, Tumor Suppressor*

Substances

  • BRCA1 Protein