Toxic metal exposures from infant diets: Risk prevention strategies for caregivers and health care professionals

Curr Probl Pediatr Adolesc Health Care. 2022 Oct;52(10):101276. doi: 10.1016/j.cppeds.2022.101276. Epub 2022 Oct 17.

Abstract

Concerns are growing regarding the presence of toxic elements such as arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb) in the ingredients and prepared foods for infants and young children. There are few clear, evidence-based, guidelines on the maximum tolerable limits of toxicants in foods and little understanding of toxicant exposure or adverse health effects attributable to dietary exposure. Caregivers are faced with the burden of making decisions about which foods to select, how often to feed them to their children, and what foods to limit. This article reviews the current literature and existing recommendations on dietary exposure to toxic elements in children under 2 years of age, and their health effects in early childhood-focusing on growth, neurodevelopment, and immune function. The article also outlines best practices for healthcare providers to address the concerns of toxic element exposure through the diet in young children. Several foods consistently appear in the literature as potential sources of toxic element exposure. Contaminated drinking and cooking water, including water used to prepare infant formula, could also be a major exposure source. In the absence of stronger evidence on effects of dietary modification, exclusive breastfeeding until six months of age, followed by a diverse diet are some strategies to reduce dietary toxic element exposure while ensuring an adequate and balanced nutrient intake. Healthcare providers can support families by sharing information and encouraging blood Pb testing, the only element for which such testing is currently recommended.

Publication types

  • Review

MeSH terms

  • Caregivers*
  • Child
  • Child, Preschool
  • Diet
  • Heavy Metal Poisoning
  • Humans
  • Infant
  • Lead / adverse effects
  • Mercury*
  • Water

Substances

  • Lead
  • Mercury
  • Water