Multifocal Ectopic Purkinje-Related Premature Contractions Syndrome in R222Q-SCN5A Gene Mutation Carriers Treated With Flecainide

JACC Clin Electrophysiol. 2022 Oct;8(10):1334-1336. doi: 10.1016/j.jacep.2022.07.008. Epub 2022 Aug 31.

Authors

Paolo Basile¹, Gianluigi Napoli¹, Matteo Anaclerio¹, Cinzia Forleo¹, Andrea Igoren Guaricci²

Affiliations

¹ University Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari "Aldo Moro," Bari, Italy.
² University Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari "Aldo Moro," Bari, Italy. Electronic address: andrea.guaricci@gmail.com.

PMID: 36266013
DOI: 10.1016/j.jacep.2022.07.008

No abstract available

Keywords: MEPPC syndrome; SCN5A gene; flecainide; ventricular arrhythmias.

MeSH terms

Anti-Arrhythmia Agents / therapeutic use
Flecainide* / therapeutic use
Humans
Mutation / genetics
NAV1.5 Voltage-Gated Sodium Channel* / genetics

Substances

Flecainide
SCN5A protein, human
NAV1.5 Voltage-Gated Sodium Channel
Anti-Arrhythmia Agents