Common Co-Morbidities in Heart Failure - Diabetes, Functional Mitral Regurgitation and Sleep Apnoea

Abstract

Heart failure (HF) is a condition that carries a considerable burden of disability many now related to co-existing co-morbidities. The drive to find newer effective therapies targeting novel mechanisms has led to a recent emphasis on treating common co-morbidities that are clustered around contemporary HF patients. Here is renewed contemporary co-morbidities that until recently have received little attention but which are now subject of considerable interest and potential therapeutic advance. These include, diabetes, functional mitral regurgitation and sleep disordered breathing. These three contemporary co-morbidities that have recently been subject to major trial evaluation will be reviewed in this paper.

Keywords: Comorbidity; Diabetes mellitus; Heart failure; Mitral regurgitation; Sleep-disordered breathing.