Antimicrobial stewardship in solid organ transplantation: Perspective from a Veterans Affairs Medical Center

Transpl Infect Dis. 2022 Oct;24(5):e13948. doi: 10.1111/tid.13948.

Abstract

Background: The importance of antimicrobial stewardship (AMS) activities specifically focused on solid organ transplant (SOT) recipients is increasingly recognized. In 2014, the Veterans Health Administration (VHA) created national guidance and committed resources to establish AMS programs at Veterans Affairs (VA) medical centers across the country. However, the AMS implementation is at the discretion of individual VA centers.

Methods: We undertook an environmental scan of AMS activities in a tertiary care VA medical center.

Results: We describe AMS activities focused on SOT recipients. Strategies based on local epidemiology that leverage the electronic medical record together with engagement by transplant infectious diseases personnel are likely to be beneficial.

Conclusion: AMS in SOT recipients is challenging yet impactful. Strategies described here may be useful for AMS activities focused on the SOT population.

Keywords: antimicrobial stewardship; organ transplant.

MeSH terms

  • Antimicrobial Stewardship*
  • Humans
  • Organ Transplantation* / adverse effects
  • Tertiary Care Centers
  • Transplants*
  • United States
  • United States Department of Veterans Affairs
  • Veterans Health Services
  • Veterans*