Successful treatment with cyclosporine and guselkumab for pityriasis rubra pilaris

Mai Nishimura; Makoto Kondo; Koji Habe; Akinobu Hayashi; Keiichi Yamanaka

doi:10.1002/ccr3.6413

Successful treatment with cyclosporine and guselkumab for pityriasis rubra pilaris

Clin Case Rep. 2022 Oct 7;10(10):e6413. doi: 10.1002/ccr3.6413. eCollection 2022 Oct.

Authors

Mai Nishimura¹, Makoto Kondo¹, Koji Habe¹, Akinobu Hayashi², Keiichi Yamanaka¹

Affiliations

¹ Department of Dermatology Mie University Graduate School of Medicine Tsu Japan.
² Department of Oncologic Pathology Mie University Graduate School of Medicine Tsu Japan.

Abstract

A man with pityriasis rubra pilaris (PRP) showed no improvement in skin symptoms despite treatment with several drugs. The patient was diagnosed as having type 1 PRP. Combination therapy with cyclosporine and guselkumab improved his skin condition. Here, we propose a novel therapeutic strategy for intractable PRP.

Keywords: IL‐23p19; cyclosporine; guselkumab; pityriasis rubra pilaris.

Publication types

Case Reports