Relationship between changes in blood pressure from summer to winter and estimated 24-hour salt excretion using spot urine: the Niigata Wellness Study

Hypertens Res. 2023 Jan;46(1):226-230. doi: 10.1038/s41440-022-01049-1. Epub 2022 Oct 16.

Abstract

A convenient way to determine salt intake is salt excretion using spot urine (e-NaCl). We measured e-NaCl at health checkups and compared results with seasonal changes in blood pressure. Among 19,732 examinees who underwent health checkups from Aug. 2012 to Mar. 2013, age, body weight and e-NaCl were measured and compared to monthly mean systolic blood pressure (SBP). Excluded were those taking antihypertensive drugs and with creatinine levels higher than 2.0 mg/dL. Also examined was salt intake (i-NaCl) by an interview survey from Aug. to Dec. 2012. Correlations with SBP were R = 0.7718 for age, R = 0.5996 for body weight, R = 0.2498 for i-NaCl and R = 0.9335 for e-NaCl. e-NaCl decreased in summer. It was presumed that the reduced burden on the kidney of salt excretion due to sweating may be related to decreases in blood pressure in summer.

Keywords: Estimated 24-hour salt excretion using spot urine; Salt intake by interview survey; Seasonal changes in blood pressure.

MeSH terms

  • Blood Pressure / physiology
  • Body Weight
  • Humans
  • Hypertension*
  • Seasons
  • Sodium Chloride
  • Sodium Chloride, Dietary*

Substances

  • Sodium Chloride, Dietary
  • Sodium Chloride