A dynamically reconfigurable liquid crystal (LC) photonic device is an important research field in modern LC photonics. We present a type of continuously tunable distributed Bragg reflector (DBR) based on LC polymer composites modulated via a novel optofluidic method. LC-templated DBR films are fabricated by photopolymerization under visible standing wave interference. The influences of the incident angle, incident light intensity, and content of ethanol as a pore-forming additive on the reflection behavior are discussed in detail. Then, the LC-templated DBR films are integrated into microfluidic channels and reversibly refilled by different organic solvents. The reconfigurable characteristics of optofluidic DBRs were demonstrated by changing the average refractive index (RI) of the mixed liquids and adjusting the flow rates, resulting in the dynamic and continuous variation of the reflection band within a specific visible light band. It is anticipated that the prototype optofluidic LC device will hopefully be applied to some specific scenarios where conventional means of regulation, such as electric, optical, and temperature fields, are unsuitable and possibly boost the development of microfluidic analysis techniques based on structural color.