Stereotactic radiosurgery for recurrent pleomorphic adenoma of the lacrimal gland: a case report

Acta Neurochir (Wien). 2023 Jan;165(1):221-224. doi: 10.1007/s00701-022-05384-7. Epub 2022 Oct 15.

Abstract

Lacrimal gland pleomorphic adenomas (LGPAs) are common, benign, and intraorbital tumours that cause exophthalmos, ptosis, and visual disturbances. The curative treatment for LGPAs is gross total resection, and radiotherapy is considered adjunctive for recurrence or an alternative for inoperable LGPAs. Stereotactic radiosurgery (SRS) can be used for precise delivery of high radiation doses to the tumour, crucial in the treatment of intra-and extracranial neoplasms. Here, we present a 95-year-old woman who had a rapidly growing, recurrent LGPA and was successfully treated with SRS. The tumour was controlled without any adverse events over 21 months following SRS. SRS is a potential alternative treatment for recurrent LGPA.

Keywords: Case report; Lacrimal gland pleomorphic adenoma; Malignant transformation; Recurrence; Stereotactic radiosurgery.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoma, Pleomorphic* / pathology
  • Adenoma, Pleomorphic* / radiotherapy
  • Adenoma, Pleomorphic* / surgery
  • Aged, 80 and over
  • Eye Neoplasms* / radiotherapy
  • Eye Neoplasms* / surgery
  • Female
  • Humans
  • Lacrimal Apparatus Diseases* / pathology
  • Lacrimal Apparatus Diseases* / radiotherapy
  • Lacrimal Apparatus Diseases* / surgery
  • Lacrimal Apparatus* / pathology
  • Lacrimal Apparatus* / surgery
  • Radiosurgery*