Healthcare resource consumption prior to asthma-related death: a nationwide descriptive study

Ther Adv Respir Dis. 2022 Jan-Dec:16:17534666221130217. doi: 10.1177/17534666221130217.

Abstract

Background: Although asthma mortality declined sharply until the mid-2000s, a stagnation in mortality has been observed over the past decade in different countries.

Objective: The objective of this study is to describe healthcare resource consumption for patients who died from asthma in France.

Method: This study was conducted using data from the French National Health Data System. Patients who died from asthma between 2013 and 2017 were identified by the ICD10 codes J45 and J46. Health care consumption data were collected. Patients were categorized into four categories according to age: ⩾75, (18-75), (12-18), (0-12). Daily doses of ICS were categorized according to GINA guidelines.

Results: A total of 3829 patients were included. No ICS or an inadequate ICS dose was observed in 43.8%, 50.6%, 48.1%, and 54.0% of patients aged ⩾75, (18-74), (12-18), and (0-12) years, respectively. Dispensation of six or more SABA canisters was observed in 37.2%, 49.0%, and 70.3% of patients aged of ⩾75, (18-75), and (12-18) years, respectively. Omalizumab dispensation rate was very low [1.1% and 2.8% in patients aged ⩾75 and (18-75) years)]. The proportion of patients with a pulmonologist office visit was 13.8% and 14.6% in patients ⩾75 and (18-75) years, respectively. A lung function test was noted in only 18.6%, 28.3%, and 25.9% of patients ⩾75, (18-75) and (12-18) years, respectively.

Conclusion: Half of the patients who died from asthma received inadequate ICS doses and only a small proportion had access to biological therapies. Less than 15% were referred to a specialist.

Keywords: asthma; consumption; death; inhaled steroids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Inhalation
  • Adrenal Cortex Hormones / therapeutic use
  • Aged
  • Anti-Asthmatic Agents* / adverse effects
  • Asthma* / drug therapy
  • Delivery of Health Care
  • France / epidemiology
  • Humans
  • Omalizumab / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents
  • Omalizumab