The combination of volumetric arc radiation therapy and boost high-dose rate interstitial brachytherapy for T3N2c tongue cancer: a technical report

Jpn J Clin Oncol. 2023 Jan 6;53(1):85-90. doi: 10.1093/jjco/hyac160.

Abstract

Currently, tongue cancers are primarily managed by surgery, and interstitial brachytherapy is only recommended for a selected group of early state T1-2N0 patients who refuse surgery or are medically inoperable. In this report, a case with T3N2cM0 tongue cancer who has been effectively treated by the combination of concurrent chemoradiotherapy involving volumetric arc therapy and boost high-dose rate interstitial brachytherapy is presented. Of course, surgery remains the main treatment strategy for tongue cancer patients; however, the authors believe that if volumetric arc therapy is carefully planned to reduce the mandible dose as much as possible and high-dose rate interstitial brachytherapy with a mouthpiece that protects the mandible is combined, it is possible to treat T3N2 disease, and this can be considered for patients who want to preserve organ function.

Keywords: HDR-ISBT boost; IMRT; T3 tongue cancer; VMAT; head and neck cancer; interstitial brachytherapy.

MeSH terms

  • Brachytherapy* / adverse effects
  • Chemoradiotherapy
  • Head
  • Humans
  • Radiotherapy Dosage
  • Tongue Neoplasms* / radiotherapy