Misdiagnosis of intramural ectopic pregnancy and invasive gestational trophoblastic disease on ultrasound: A challenging case at Tu Du Hospital in Vietnam in COVID-19 pandemic peak and mini-review of literature

Radiol Case Rep. 2022 Oct 7;17(12):4821-4827. doi: 10.1016/j.radcr.2022.09.034. eCollection 2022 Dec.

Abstract

Differentiation between intramural ectopic pregnancy and molar ectopic pregnancy is very difficult because of their exceptional rarity. Herein, we present a misdiagnosed case of intramural pregnancy and invasive trophoblastic disease on ultrasound. A 45-year-old female patient was admitted to our tertiary referral hospital due to abdominal pain and unusual ultrasonography findings. Initially, a diagnosis of intramural ectopic pregnancy was identified based on transvaginal color Doppler ultrasonography, 3-dimensional ultrasound, and serial serum beta-human chorionic gonadotropin, thus the patient underwent laparotomy with hysterectomy. However, the histopathological endpoint showed an invasive trophoblastic disease. Clinically, this pathology should be included in the differential diagnosis of intramural ectopic pregnancy since an imaging scan remains quite unclear.

Keywords: Adenomyosis; COVID-19, coronavirus disease of 2019; Coronavirus; Doppler ultrasound; Ectopic pregnancy; GS, gestational sac; GTD, gestational trophoblastic disease; Gestational trophoblastic disease; Human chorionic gonadotropin; Hysterectomy; IEP, intramural ectopic pregnancy; TV-CDU, transvaginal color Doppler ultrasound; β-hCG, beta-human chorionic gonadotrophin.

Publication types

  • Case Reports