Therapeutic and Nutraceutical Effects of Polyphenolics from Natural Sources

Molecules. 2022 Sep 22;27(19):6225. doi: 10.3390/molecules27196225.

Abstract

The prevalence of cardiovascular disease, oxidative stress-related complications, and chronic age-related illnesses is gradually increasing worldwide. Several causes include the ineffectiveness of medicinal treatment therapies, their toxicity, their inability to provide radical solutions in some diseases, and the necessity of multiple drug therapy in certain chronic diseases. It is therefore necessary for alternative treatment methods to be sought. In this review, polyphenols were identified and classified according to their chemical structure, and the sources of these polyphenol molecules are indicated. The cardioprotective, ROS scavenging, anti-aging, anticancer properties of polyphenolic compounds have been demonstrated by the results of many studies, and these natural antioxidant molecules are potential alternative therapeutic agents.

Keywords: anti-aging; atherosclerosis; cardioprotective; oxidative stress; reactive oxygen species.

Publication types

  • Review

MeSH terms

  • Antioxidants* / chemistry
  • Dietary Supplements
  • Oxidative Stress
  • Polyphenols* / chemistry
  • Reactive Oxygen Species / pharmacology

Substances

  • Antioxidants
  • Polyphenols
  • Reactive Oxygen Species

Grants and funding

This research received no external funding.