Particularities of Catheter Ablation in Women with Atrial Fibrillation and Associated Ischemic Heart Disease

J Clin Med. 2022 Sep 22;11(19):5568. doi: 10.3390/jcm11195568.

Abstract

Background: Atrial fibrillation is more common in men, but in the presence of ischemic heart disease, this arrhythmia is more frequent in women. However, like in coronary heart disease, women with atrial fibrillation are suboptimally treated.

Methods: To identify particularities of ablation, in women with atrial fibrillation and ischemic heart disease.

Results: 29 women and 26 men, with documented ischemic heart disease and atrial fibrillation, who underwent catheter ablation, were admitted in the study. No significant differences were registered regarding the heart rate control treatment. Electrical cardioversion was significantly higher in men, while pharmacological cardioversion was predominantly recommended in women. The ablation was performed later in women, after 2.55 ± 1.84 years versus 1.80 ± 1.05 in men (p = 0.05). The time elapsed until the ablation was performed was statistically correlated with atypical symptomatology and with the number of antiarrhythmics used prior to the ablation. There were no significant differences for the relapse of atrial fibrillation at 3 months. Quality of life at 3 months after ablation was increased in both groups.

Conclusion: Catheter ablation is performed much later in women, and the causes responsible for this delay would be more atypical symptoms and a greater number of antiarrhythmics tried before the ablation.

Keywords: atrial fibrillation; catheter ablation; female sex; ischemic heart disease.

Grants and funding

This research received no external funding.