Induction of tyrosine aminotransferase by dibutyryl cyclic-AMP in synchronized hepatoma cells

Cell Biol Int Rep. 1979 May;3(3):247-55. doi: 10.1016/0309-1651(79)90037-7.

Abstract

In Hepatoma Tissue Culture (HTC) cells induction of tyrosine aminotransferase (TAT) by dibutyryl cAMP (DBcAMP) is regulated at some posttranscriptional step. In synchronized HTC cells TAT can be induced by DBcAMP in late G1 and in the S phase of the cell cycle only.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Bucladesine / pharmacology*
  • Cell Cycle
  • Cells, Cultured
  • Enzyme Induction / drug effects
  • Liver Neoplasms, Experimental / drug therapy
  • Liver Neoplasms, Experimental / enzymology*
  • Liver Neoplasms, Experimental / pathology
  • Rats
  • Tyrosine Transaminase / biosynthesis*

Substances

  • Bucladesine
  • Tyrosine Transaminase