Topical Liposomal Amphotericin (Ambisome®) for the Treatment of Cutaneous Fusarium in a Burn-Injured Patient

J Burn Care Res. 2023 Jan 5;44(1):207-209. doi: 10.1093/jbcr/irac152.

Abstract

Cutaneous Fusarium infections carry significant morbidity and mortality in burn-injured patients. Treatment involves surgical source control in combination of systemic and topical therapy. Given drug shortage constraints with conventional amphotericin deoxycholate, we describe the first case of successful treatment with adjunctive topical liposomal amphotericin in a critically ill burn-injured patient.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / adverse effects
  • Amphotericin B / therapeutic use
  • Antifungal Agents / adverse effects
  • Antifungal Agents / therapeutic use
  • Burns* / complications
  • Burns* / drug therapy
  • Fusarium*
  • Humans
  • Liposomes

Substances

  • liposomal amphotericin B
  • Amphotericin B
  • Liposomes
  • Antifungal Agents